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1

Oxidized galectin-1 advances the functional recovery after peripheral nerve injury

Toshihiko Kadoya, Kiyomitsu Oyanagi, Emiko Kawakami, Mitsuhiro Hasegawa, Yoshimasa Inagaki, Yoshiaki Sohma, Hidenori Horie

Journal:

Neuroscience Letters

Year:

2005

Language:

english

File:

PDF, 213 KB

english, 2005

2

The First 0.14-dB/km Loss Optical Fiber and its Impact on Submarine Transmission

Tamura, Yoshiaki, Sakuma, Hirotaka, Morita, Keisei, Suzuki, Masato, Yamamoto, Yoshinori, Shimada, Kensaku, Honma, Yuya, Sohma, Kazuyuki, Fujii, Takashi, Hasegawa, Takemi

Journal:

Journal of Lightwave Technology

Year:

2018

Language:

english

File:

PDF, 87 KB

english, 2018

3

Galectin-1 Regulates Initial Axonal Growth in Peripheral Nerves after Axotomy

Horie, Hidenori, Inagaki, Yoshimasa, Sohma, Yoshiaki, Nozawa, Risa, Okawa, Katsuya, Hasegawa, Mitsuhiro, Muramatsu, Naoki, Kawano, Hitoshi, Horie, Masao, Koyama, Hiromichi, Sakai, Ikuko, Takeshita, Ka

Journal:

Journal of Neuroscience

Year:

1999

Language:

english

File:

PDF, 1.81 MB

english, 1999

4

ON intramolecular acyl migration reaction in the development of prodrugs and the synthesis of difficult sequence-containing bioactive peptides

Youhei Sohma, Yoshio Hayashi, Mariusz Skwarczynski, Yoshio Hamada, Masato Sasaki, Tooru Kimura, Yoshiaki Kiso

Journal:

Year:

2004

Language:

english

File:

PDF, 548 KB

english, 2004

5

Development of O-acyl isopeptide method

Youhei Sohma, Taku Yoshiya, Atsuhiko Taniguchi, Tooru Kimura, Yoshio Hayashi, Yoshiaki Kiso

Journal:

Year:

2007

Language:

english

File:

PDF, 424 KB

english, 2007

6

S-acyl isopeptide method: Use of allyl-type protective group for improved preparation of thioester-containing S-acyl isopeptides by Fmoc-based SPPS

Taku Yoshiya, Yuka Hasegawa, Wakana Kawamura, Hiroyuki Kawashima, Youhei Sohma, Tooru Kimura, Yoshiaki Kiso

Journal:

Year:

2011

Language:

english

File:

PDF, 929 KB

english, 2011

7

“Click Peptides”—Chemical Biology-Oriented Synthesis of Alzheimer's Disease-Related Amyloid β Peptide (Aβ) Analogues Based on the “O-Acyl Isopeptide Method”

Youhei Sohma, Yoshiaki Kiso

Journal:

Year:

2006

Language:

english

File:

PDF, 452 KB

english, 2006

8

Controlled Production of Amyloid β Peptide from a Photo-Triggered, Water-Soluble Precursor “Click Peptide“

Atsuhiko Taniguchi, Mariusz Skwarczynski, Youhei Sohma, Takuma Okada, Keisuke Ikeda, Halan Prakash, Hidehito Mukai, Yoshio Hayashi , Tooru Kimura, Shun Hirota, Katsumi Matsuzaki, Yoshiaki Kiso

Journal:

Year:

2008

Language:

english

File:

PDF, 660 KB

english, 2008

9

“Click Peptide“: pH-Triggered in Situ Production and Aggregation of Monomer Aβ1–42

Atsuhiko Taniguchi , Youhei Sohma, Yuta Hirayama, Hidehito Mukai, Tooru Kimura, Yoshio Hayashi , Katsumi Matsuzaki, Yoshiaki Kiso

Journal:

Year:

2009

Language:

english

File:

PDF, 421 KB

english, 2009

10

Click Peptide Concept: O-Acyl Isopeptide of Islet Amyloid Polypeptide as a Nonaggregative Precursor Molecule

Dr. Taku Yoshiya, Ayano Higa, Naoko Abe, Fukue Fukao, Tomomi Kuruma, Yuki Toda, Prof. Dr. Youhei Sohma, Prof. Dr. Yoshiaki Kiso

Journal:

Year:

2011

Language:

english

File:

PDF, 413 KB

english, 2011

11

ChemInform Abstract: Controlled Drug Release: New Water-Soluble Prodrugs of an HIV Protease Inhibitor.

Hikaru Matsumoto, Youhei Sohma, Tooru Kimura, Yoshio Hayashi, Yoshiaki Kiso

Journal:

Year:

2001

File:

PDF, 29 KB

2001

12

O—N Intramolecular Acyl Migration Strategy in Water-Soluble Prodrugs of Taxoids.

Mariusz Skwarczynski, Youhei Sohma, Maiko Kimura, Yoshio Hayashi, Tooru Kimura, Yoshiaki Kiso

Journal:

Year:

2004

File:

PDF, 123 KB

2004

13

‘O-Acyl isopeptide method’ for the efficient preparation of amyloid β peptide 1–42 mutants

Youhei Sohma, Yousuke Chiyomori, Maiko Kimura, Fukue Fukao, Atsuhiko Taniguchi, Yoshio Hayashi, Tooru Kimura, Yoshiaki Kiso

Journal:

Bioorganic & Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 217 KB

english, 2005

14

Self-assembly pathways of E22Δ-type amyloid β peptide mutants generated from non-aggregative O-acyl isopeptide precursors

Youhei Sohma, Hui Wang, Atsuhiko Taniguchi, Yuta Hirayama, Taeko Kakizawa, Moe Yamasaki, Hidehito Mukai, Yoshiaki Kiso

Journal:

Bioorganic & Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 576 KB

english, 2011

15

‘Click peptide’ using production of monomer Aβ from the O-acyl isopeptide: Application to assay system of aggregation inhibitors and cellular cytotoxicity

Youhei Sohma, Yuta Hirayama, Atsuhiko Taniguchi, Hidehito Mukai, Yoshiaki Kiso

Journal:

Bioorganic & Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 535 KB

english, 2011

16

Development of first photoresponsive prodrug of paclitaxel

Mariusz Skwarczynski, Mayo Noguchi, Shun Hirota, Youhei Sohma, Tooru Kimura, Yoshio Hayashi, Yoshiaki Kiso

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 308 KB

english, 2006

17

Design and synthesis of a novel water-soluble Aβ1-42 isopeptide: an efficient strategy for the preparation of Alzheimer's disease-related peptide, Aβ1-42, via O–N intramolecular acyl migration reaction

Youhei Sohma, Masato Sasaki, Yoshio Hayashi, Tooru Kimura, Yoshiaki Kiso

Journal:

Tetrahedron Letters

Year:

2004

Language:

english

File:

PDF, 282 KB

english, 2004

18

‘O-Acyl isopeptide method’ for the efficient synthesis of difficult sequence-containing peptides: use of ‘O-acyl isodipeptide unit’

Youhei Sohma, Atsuhiko Taniguchi, Mariusz Skwarczynski, Taku Yoshiya, Fukue Fukao, Tooru Kimura, Yoshio Hayashi, Yoshiaki Kiso

Journal:

Tetrahedron Letters

Year:

2006

Language:

english

File:

PDF, 165 KB

english, 2006

19

‘O-Acyl isopeptide method’: racemization-free segment condensation in solid phase peptide synthesis

Taku Yoshiya, Youhei Sohma, Tooru Kimura, Yoshio Hayashi, Yoshiaki Kiso

Journal:

Tetrahedron Letters

Year:

2006

Language:

english

File:

PDF, 187 KB

english, 2006

20

Synthesis of the sphingolipid activator protein, saposin C, using an azido-protected O-acyl isopeptide as an aggregation-disrupting element

Hironobu Hojo, Hidekazu Katayama, Chiharu Tano, Yuko Nakahara, Azusa Yoneshige, Junko Matsuda, Youhei Sohma, Yoshiaki Kiso, Yoshiaki Nakahara

Journal:

Tetrahedron Letters

Year:

2011

Language:

english

File:

PDF, 617 KB

english, 2011

21

Controlled drug release: new water-soluble prodrugs of an HIV protease inhibitor

Hikaru Matsumoto, Youhei Sohma, Tooru Kimura, Yoshio Hayashi, Yoshiaki Kiso

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2001

Language:

english

File:

PDF, 190 KB

english, 2001

22

New water-soluble prodrugs of HIV protease inhibitors based on O→N intramolecular acyl migration

Yoshio Hamada, Jun Ohtake, Youhei Sohma, Tooru Kimura, Yoshio Hayashi, Yoshiaki Kiso

Journal:

Bioorganic & Medicinal Chemistry

Year:

2002

Language:

english

File:

PDF, 288 KB

english, 2002

23

Oxidized galectin-1 promotes axonal regeneration in peripheral nerves but does not possess lectin properties

Yoshimasa Inagaki, Yoshiaki Sohma, Hidenori Horie, Risa Nozawa, Toshihiko Kadoya

Journal:

Year:

2000

Language:

english

File:

PDF, 884 KB

english, 2000

24

Neuropsychological Changes After Surgical Treatment for Temporal Lobe Epilepsy

Manabu Wachi, Masaru Tomikawa, Masafumi Fukuda, Shigeki Kameyama, Kazuhiko Kasahara, Mutsuo Sasagawa, Seiko Shirane, Osamu Kanazawa, Mihoko Yoshino, Satsuki Aoki, Yoshiaki Sohma

Journal:

Year:

2001

Language:

english

File:

PDF, 121 KB

english, 2001

25

Epimerization-free synthesis of cyclic peptide by use of the O-acyl isopeptide method

Taku Yoshiya, Hiroyuki Kawashima, Yuka Hasegawa, Kazuhiro Okamoto, Tooru Kimura, Youhei Sohma, Yoshiaki Kiso

Journal:

Journal of Peptide Science

Year:

2010

Language:

english

File:

PDF, 234 KB

english, 2010

26

The ‘O-acyl isopeptide method’ for the synthesis of difficult sequence-containing peptides: application to the synthesis of Alzheimer's disease-related amyloid β peptide (Aβ) 1–42

Youhei Sohma, Yoshio Hayashi, Maiko Kimura, Yousuke Chiyomori, Atsuhiko Taniguchi, Masato Sasaki, Tooru Kimura, Professor Yoshiaki Kiso

Journal:

Journal of Peptide Science

Year:

2005

Language:

english

File:

PDF, 226 KB

english, 2005

27

‘O-Acyl isopeptide method’ for peptide synthesis: Solvent effects in the synthesis of Aβ1–42 isopeptide using ‘O-acyl isodipeptide unit’

Atsuhiko Taniguchi, Taku Yoshiya, Naoko Abe, Fukue Fukao, Youhei Sohma, Tooru Kimura, Yoshio Hayashi, Yoshiaki Kiso

Journal:

Journal of Peptide Science

Year:

2007

Language:

english

File:

PDF, 278 KB

english, 2007

28

O–N Intramolecular acyl migration strategy in water-soluble prodrugs of taxoids

Mariusz Skwarczynski, Youhei Sohma, Maiko Kimura, Yoshio Hayashi, Tooru Kimura, Yoshiaki Kiso

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2003

Language:

english

File:

PDF, 167 KB

english, 2003

29

Structure-guided design and synthesis of position 1-phenylcycloalkylamine-derived pentapeptidic BACE1 inhibitors

Harichandra D. Tagad, Yoshio Hamada, Jeffrey-Tri Nguyen, Koushi Hidaka, Takashi Hamada, Youhei Sohma, Tooru Kimura, Yoshiaki Kiso

Journal:

Bioorganic & Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 855 KB

english, 2011

30

CD52 is a novel costimulatory molecule for induction of CD4+ regulatory T cells

Tomoko Watanabe, Jun-ichi Masuyama, Yoshiaki Sohma, Hiroko Inazawa, Kaori Horie, Kumiko Kojima, Yasunori Uemura, Yumi Aoki, Shuji Kaga, Seiji Minota, Toshiyuki Tanaka, Yasunori Yamaguchi, Tetsuto Koba

Journal:

Clinical Immunology

Year:

2006

Language:

english

File:

PDF, 603 KB

english, 2006

31

Synthesis of an O-acyl isopeptide by using native chemical ligation to efficiently construct a hydrophobic polypeptide

Youhei Sohma, Hitomi Kitamura, Hiroyuki Kawashima, Hironobu Hojo, Masayuki Yamashita, Kenichi Akaji, Yoshiaki Kiso

Journal:

Tetrahedron Letters

Year:

2011

Language:

english

File:

PDF, 280 KB

english, 2011

32

Molecular cloning and chromosomal localization of the human thrombopoietin gene

Yoshiaki Sohma, Hiromichi Akahori, Naohiko Seki, Tada-aki Hori, Kinya Ogami, Takashi Kato, Yoshihiro Shimada, Kazuo Kawamura, Hiroshi Miyazaki

Journal:

Year:

1994

Language:

english

File:

PDF, 1.04 MB

english, 1994

33

The sequence of a rat cDNA encoding thrombopoietin

Kinya Ogami, Yoshihiro Shimada, Yoshiaki Sohma, Hiromichi Akahori, Takashi Kato, Kazuo Kawamura, Hiroshi Miyazaki

Journal:

Year:

1995

Language:

english

File:

PDF, 179 KB

english, 1995

34

Design, synthesis, and biophysical properties of a helical Aβ1–42 analog: Inhibition of fibrillogenesis and cytotoxicity

Katsumi Matsuzaki, Takuma Okada, Miho Tsukuda, Keisuke Ikeda, Youhei Sohma, Yousuke Chiyomori, Atsuhiko Taniguchi, Setsuko Nakamura, Nui Ito, Yoshio Hayashi, Yoshiaki Kiso

Journal:

Biochemical and Biophysical Research Communications

Year:

2008

Language:

english

File:

PDF, 595 KB

english, 2008

35

Expression profile analysis of aorta-gonad-mesonephros region-derived stromal cells reveals genes that regulate hematopoiesis

Kenji Nagao, Takayuki Ohta, Atsushi Hinohara, Tomoyuki Tahara, Tetsuya Hagiwara, Yoshitake Maeda, Takashi Yoneya, Yoshiaki Sohma, Toshio Heike, Tatsutoshi Nakahata, Yoshimasa Inagaki, Mitsuo Nishikawa

Journal:

Biochemical and Biophysical Research Communications

Year:

2008

Language:

english

File:

PDF, 466 KB

english, 2008

36

COS 1 cell secretes a factor to promote neurite regeneration from transected-nerve terminals of cultured adult DRG

Hidenori Horie, Toshihiko Kadoya, Yoshimasa Inagaki, Yoshiaki Sohma, Risa Nozawa, Hitoshi Kawano, Masao Horie, Ikuko Sakai, Kaori Takeshita, Yuki Kowada, Mitsuhiro Hasegawa, Naoki Muramatsu, Masahiko

Journal:

Neuroscience Research

Year:

1998

Language:

english

File:

PDF, 86 KB

english, 1998

37

Plasmacytoid dendritic cells: from specific surface markers to specific cellular functions

Andrzej Dzionek, Yoshimasa Inagaki, Katsuya Okawa, Jun Nagafune, J.ürgen Röck, Yoshiaki Sohma, Gregor Winkels, Monika Zysk, Yasunori Yamaguchi, J.ürgen Schmitz

Journal:

Human Immunology

Year:

2002

Language:

english

File:

PDF, 501 KB

english, 2002

38

O−N Intramolecular Alkoxycarbonyl Migration of Typical Protective Groups in Hydroxyamino Acids

Skwarczynski, Mariusz, Sohma, Youhei, Noguchi, Mayo, Kimura, Tooru, Hayashi, Yoshio, Kiso, Yoshiaki

Journal:

Journal of Organic Chemistry

Year:

2006

Language:

english

File:

PDF, 61 KB

english, 2006

39

O-Acyl isopeptide method: efficient synthesis of isopeptide segment and application to racemization-free segment condensation

Yoshiya, Taku, Kawashima, Hiroyuki, Sohma, Youhei, Kimura, Tooru, Kiso, Yoshiaki

Journal:

Organic & Biomolecular Chemistry

Year:

2009

Language:

english

File:

PDF, 3.44 MB

english, 2009

40

?O-Acyl isopeptide method? for peptide synthesis: synthesis of forty kinds of ?O-acyl isodipeptide unit? Boc-Ser/Thr(Fmoc-Xaa)-OH

Yoshiya, Taku, Taniguchi, Atsuhiko, Sohma, Youhei, Fukao, Fukue, Nakamura, Setsuko, Abe, Naoko, Ito, Nui, Skwarczynski, Mariusz, Kimura, Tooru, Hayashi, Yoshio, Kiso, Yoshiaki

Journal:

Organic & Biomolecular Chemistry

Year:

2007

Language:

english

File:

PDF, 271 KB

english, 2007

41

No Auxiliary, No Byproduct Strategy for Water-Soluble Prodrugs of Taxoids: Scope and Limitation of O−N Intramolecular Acyl and Acyloxy Migration Reactions †

Skwarczynski, Mariusz, Sohma, Youhei, Noguchi, Mayo, Kimura, Maiko, Hayashi, Yoshio, Hamada, Yoshio, Kimura, Tooru, Kiso, Yoshiaki

Journal:

Journal of Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 240 KB

english, 2005

42

A new class of aggregation inhibitor of amyloid-β peptide based on an O-acyl isopeptide

Kawashima, Hiroyuki, Sohma, Youhei, Nakanishi, Tomoya, Kitamura, Hitomi, Mukai, Hidehito, Yamashita, Masayuki, Akaji, Kenichi, Kiso, Yoshiaki

Journal:

Bioorganic & Medicinal Chemistry

Year:

2013

Language:

english

File:

PDF, 1.73 MB

english, 2013

43

Comparative properties of Aβ1–42, Aβ11–42, and [Pyr11]Aβ11–42 generated from O-acyl isopeptides

Sohma, Youhei, Yamasaki, Moe, Kawashima, Hiroyuki, Taniguchi, Atsuhiko, Yamashita, Masayuki, Akaji, Kenichi, Mukai, Hidehito, Kiso, Yoshiaki

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2013

Language:

english

File:

PDF, 617 KB

english, 2013

44

Novel and efficient synthesis of difficult sequence-containing peptides through O?N intramolecular acyl migration reaction of O-acyl isopeptidesElectronic Supplementary Information (ESI) available: HPLC profiles of crude state, migration studies, and spectral data for 1, 5, 6, and 7. See http://www.rsc.org/suppdata/cc/b3/b312129a/

Sohma, Youhei, Sasaki, Masato, Hayashi, Yoshio, Kimura, Tooru, Kiso, Yoshiaki

Journal:

Chemical Communications

Year:

2004

Language:

english

File:

PDF, 165 KB

english, 2004

45

“Click Peptide” Based on the “ O- Acyl Isopeptide Method”: Control of Aβ1−42 Production from a Photo-Triggered Aβ1−42 Analogue

Taniguchi, Atsuhiko, Sohma, Youhei, Kimura, Maiko, Okada, Takuma, Ikeda, Keisuke, Hayashi, Yoshio, Kimura, Tooru, Hirota, Shun, Matsuzaki, Katsumi, Kiso, Yoshiaki

Journal:

Journal of the American Chemical Society

Year:

2006

Language:

english

File:

PDF, 59 KB

english, 2006

46

Development of Water-Soluble Prodrugs of the HIV-1 Protease Inhibitor KNI-727: Importance of the Conversion Time for Higher Gastrointestinal Absorption of Prodrugs Based on Spontaneous Chemical Cleavage

Sohma, Youhei, Hayashi, Yoshio, Ito, Tomoko, Matsumoto, Hikaru, Kimura, Tooru, Kiso, Yoshiaki

Journal:

Journal of Medicinal Chemistry

Year:

2003

Language:

english

File:

PDF, 171 KB

english, 2003

47

A Novel Approach of Water-Soluble Paclitaxel Prodrug with No Auxiliary and No Byproduct: Design and Synthesis of Isotaxel

Hayashi, Yoshio, Skwarczynski, Mariusz, Hamada, Yoshio, Sohma, Youhei, Kimura, Tooru, Kiso, Yoshiaki

Journal:

Journal of Medicinal Chemistry

Year:

2003

Language:

english

File:

PDF, 54 KB

english, 2003

48

Non-pretreated O-acyl isopeptide of amyloid β peptide 1–42 is monomeric with a random coil structure but starts to aggregate in a concentration-dependent manner

Yoshiya, Taku, Maruno, Takahiro, Uemura, Tsuyoshi, Kubo, Shigeru, Kiso, Yoshiaki, Sohma, Youhei, Yoshizawa-Kumagaye, Kumiko, Kobayashi, Yuji, Nishiuchi, Yuji

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2014

Language:

english

File:

PDF, 818 KB

english, 2014

49

Synthesis of O -Acyl Isopeptides

Sohma, Youhei, Kiso, Yoshiaki

Journal:

The Chemical Record

Year:

2013

Language:

english

File:

PDF, 293 KB

english, 2013

50

O -Acyl isopeptide method: development of an O -acyl isodipeptide unit for Boc SPPS and its application to the synthesis of A β 1-42 isopeptide

Yoshiya, Taku, Uemura, Tsuyoshi, Maruno, Takahiro, Kubo, Shigeru, Kiso, Yoshiaki, Sohma, Youhei, Kobayashi, Yuji, Yoshizawa-Kumagaye, Kumiko, Nishiuchi, Yuji

Journal:

Journal of Peptide Science

Year:

2014

Language:

english

File:

PDF, 530 KB

english, 2014